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Reversing Biologial Clock an Acheivebale Goal!

Srinivasa K. Rao, Ph.D.
3 min readAug 23, 2024

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The Fountain of Youth article was published in 1905 by Washburn Hopkins in the Journal of the American Oriental Society. It's a review of human aspiration to reverse aging since ancient times. In his article, he mentions the story of King Yayati exchanging his old age with his young son Puru from Mahabharata, the Indian Epic Mahabharata. The Mahabharata period is between 3,000- 4,000 BC, according to research by Subhash Kak. The idea of getting the youth from young to old to reverse aging is an age-old wish.

In groundbreaking experiments, Dr. Vadim N. Gladyshev's lab at Harvard Medical School attached the blood vessels of old and young mice to have a continuous circulation of blood between the young and old mice to study the effect of young mice's blood on the old mice. The results show that there is a drastic reduction biological age of old mice. The reduction in biological age persisted even after 2 months of detachment. A profound decrease in epigenetic age, ranging from 19–28% in different tissues, is observed. Blood cell transplantation was shown to be effective as well. The implications of these and other similar findings are staggering, suggesting that similar techniques or the knowledge gained in these experiments could one day be applied to humans for reversing biological aging and even increasing lifespan. Research from several labs with different rejuvenation strategies shows that it's an achievable goal. These scientific advancements have brought the desire of humans to reverse aging and gain youthfulness one step…

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Srinivasa K. Rao, Ph.D.
Srinivasa K. Rao, Ph.D.

Written by Srinivasa K. Rao, Ph.D.

Biomedical Scientist in New York is interested in Nutrition, Metabolomics, Food as Medicine, STEM and AI. https://www.linkedin.com/in/sraonewyrok/

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